Effect of cyclosporine A and tacrolimus on OATP1B1 mediated transport of atorvastatin in an in vitro whole cell model

of Oslo, under supervision of Professor Anders Åsberg and PhD student Rune Amundsen. I would like to express my gratitude to my first supervisor, Anders Åsberg, for his outstanding contribution and support during the entire period of work on this thesis. His valuable suggestions and advice were always greatly appreciated. My special thanks and gratefulness goes to Rune Amundsen, his optimism, dedication and thoughtfulness cannot be appreciated highly enough. His patience, even when things went really wrong, has been of major importance for carrying out this study. Furthermore, I would like to thank Siri Johanessen and Beata Mohebi for always taking the time to help me, and for teaching me many of the laboratory techniques. I owe a special thanks to my in-house supervisor at the School of Pharmacy, University of Tromsø, Professor Thrina Loennechen, for good advice, kindness and understanding not only during this year, but during my entire study time in Tromsø. I greatly appreciate everything you did for me in helping me through my studies. Finally I would like to thank my family for their endless love and understanding. Many thanks to dear mum and dad, my brother Behzad and my lovely sister Elnaz for their invaluable support. Thanks to my dear husband Bahman for never-ending love, continuous support, encouragement and understanding. I could not have finished this thesis without them, who always bring so much joy into my life and remind me of the issues that are most important in life.